A database of hormones and their receptors| A database of hormones and their receptors |
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| HMRbase accession number | 10510 |
| Swiss-prot Accession number | Q66Q82 (Sequence in FASTA format) |
| Description | Bursicon precursor (Bursicon subunit alpha) (Cuticle-tanning hormone). |
| Source organism | Anopheles gambiae (African malaria mosquito) |
| Taxonomical Classification | Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;Anophelinae; Anopheles. |
| Subcellular location | Secreted protein (By similarity) |
| Developmental Stage | N/A |
| Similarity | Contains 1 CTCK (C-terminal cystine knot-like) domain. |
| Tissue Specificity | N/A |
| Post translational modification | N/A |
| Function | Final heterodimeric neurohormone released at the end of the molting cycle, involved in the sclerotization (tanning) of the insect cuticle, melanization and wing spreading |
| Protein Length | 163 Amino acids |
| Molecular weight | 18067 |
| References | 1 Robertson H.M., Honegger W.; "Anopheles gambiae bursicon gene is transspliced."; Submitted (AUG-2004) to the EMBL/GenBank/DDBJ databases.
2 PubMed abstract 12364791 |
| Domain Name | N/A |
| Hormone Name | Bursicon |
| Mature Hormone Sequence | QKDSEDGGSHYSSDDCQVTPVIHVLQYPGCVPKPIPSFACIGRCASYIQVSGSKIWQMERSCMCCQESGEREASVSLFCPKAKNGEKKFRKVSTKAPLECMCRPCTGIEDANVIPQELTSFADEGTLTGYFQKSHYKSIE |
| Position of mature hormone in Pre-Hormone protein | 140 Residues from position (24-163) |
| Receptor | N/A |
| Gene ID | 5667449 |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments | !Receptor for this Hormone are either unknown or have not yet been curated |